Searchable abstracts of presentations at key conferences in endocrinology

ea0073ep217 | Thyroid | ECE2021

Thyroid dysfunction associated with immune checkpoint inhibitors therapy

Mazurina Natalya , Glibka Anastasiya , Troshina Ekaterina , Laktionov Konstantine , Kharkevich Galina , Sarantseva Kseniya , Kruteleva Svetlana

IntroductionProspective and retrospective trials report the incidence of endocrine adverse events provoked by immune checkpoint inhibitors (ICI) up to 30%. PD-1/PDL inhibitors have a higher incidence of thyroid dysfunction: hypothyroidism 5%-14%, transient hyperthyroidism – 3%-5%.The aim of the study was to assess thyroid function in PD-1/PDL treated patients.Materials and methods6...